‘I Am Not Misinformation’ – Compelling Stories Told By The Vaxxed Injured

Read the Fine Print, Part Two—Nearly 400 Adverse Reactions Listed in Vaccine Package Inserts

By Children’s Health Defense Team

Package inserts are available online for all vaccines licensed in the U.S. In addition to containing bits of practical information for the clinicians who administer the vaccines, the inserts provide members of the public with one of their only opportunities to learn about a vaccine’s contraindications, warnings, precautions and—perhaps most importantly—potential adverse reactions.

The inserts communicate the information about adverse reactions in two distinct sections: “Clinical trials experience” (Section 6.1) and “Data from postmarketing experience” from the U.S. or other countries (Section 6.2). In April, 2020, Children’s Health Defense summarized the postmarketing data for over three dozen vaccines given routinely to American infants, children and adolescents. That tally showed that vaccines touted for the prevention of 13 illnesses (Table 1) have been linked to at least 217 adverse medical outcomes reported post-licensure, including serious infections, autoimmune conditions, life-threatening allergies and death.

As noted in April, the postmarketing list is far from exhaustive, because manufacturers have the latitude to decide which outcomes to list in the inserts—using loose criteria determined by severity, frequency of reporting and “strength of evidence for a causal relationship.” In addition, vaccine adverse events are notoriously underreported, not least because medical schools do not teach doctors to recognize vaccine injuries. But what would the picture look like if the adverse reactions observed during clinical trials were also added to the list?This combination of clinical trial and postmarketing data presents a dramatic picture, with almost double the total number of undesirable post-vaccination outcomes …

Double trouble

Children’s Health Defense can now answer that question. The revised chart (Table 2) includes the adverse reactions reported in the clinical trial sections of 41 vaccine brands covering diphtheria, Haemophilus influenzae type b, hepatitis A, hepatitis B, human papillomavirus, influenza, meningococcal infection, pertussis, pneumococcal infection, polio, rotavirus, tetanus and varicella. This combination of clinical trial and postmarketing data presents a dramatic picture, with almost double the total number of undesirable post-vaccination outcomes—397 different types of reactions reported pre- and post-licensure.

Although roughly 400 adverse events is a sobering number, again, it is probably an underestimate. This is because most clinical trials follow participants for an absurdly short period of time—three days here, seven days there—and do not capture problems that arise beyond that brief window, even though clinicians recognize (and the scientific literature confirms) that vaccine reactions are not always immediate or acute. Moreover, even for those few days of monitoring, the inserts are often short on details, citing only a smattering of adverse events collected from a predetermined list of “solicited” reactions and only sometimes accepting “unsolicited” feedback. In addition, the fact that vaccine clinical trials typically compare vaccine against vaccine rather than vaccine against inert placebo makes it easy to divert attention from specific adverse reactions by simply citing “similar rates” of adverse reactions in both groups.… and that vaccines can cause the very illnesses—or adverse consequences of those illnesses—that they are supposed to prevent.

Clinical trial themes

The April discussion of postmarketing adverse events noted several themes, including the facts that all vaccines are capable of producing adverse reactions (though Gardasil and Gardasil 9 are macabre standouts) and that vaccines can cause the very illnesses—or adverse consequences of those illnesses—that they are supposed to prevent. The clinical trial data reinforce these points and also highlight some new themes:

• The adverse reactions reported following clinical trials do not necessarily match up to the adverse reactions reported post-licensure. This is particularly the case for vaccine-associated deaths; whereas the April postmarketing-only list included just two categories of death associated with six vaccines, the addition of clinical trial data brings the total up to 40 types of death associated with 13 vaccines.
• Sizeable proportions of participants in vaccine clinical trials experience unpleasant reactions, including fever, chills, pain, nausea, diarrhea, vomiting, headache, rash, loss of appetite and irritability.  For example, in clinical trials for the five-pronged Pentacel vaccine (diphtheria, tetanus, pertussis, Haemophilus influenzae type b and polio)—given as a four-dose series beginning at six weeks of age—almost half of the young children (48%) experienced injection-site “tenderness” after the first dose (defined as “whimpering” or crying when the arm or leg was touched or moved); about the same percentage (46%) experienced “lethargy,” 59% cried “inconsolably” and 77% were “fussy” or “irritable.” In adolescents, the Adacel vaccine given as a booster for tetanus-diphtheria-acellular pertussis (Tdap) produced injection-site pain in almost eight in ten teens (78%), and one in five (20%) study participants experienced pain rated as “moderate to severe.” More than two-fifths (44%) suffered from headaches.
• Clinical trials also document more serious reactions with the potential to cause longer-term problems. Adverse reactions of particular concern—especially in the young—include asthma, seizures, heart problems, sleep problems and joint and muscle pain. Nine vaccines list anorexia as a clinical trial reaction. Surprisingly, while numerous package inserts mention serious and potentially lifelong conditions like transverse myelitis (11 vaccines) and Guillain-Barré syndrome (20 vaccines) in their postmarketing section, only a few list them as a clinical trial outcome despite hundreds of published studies pointing to post-vaccination onset.
• Intentional and unintentional injuries are more prominent in the clinical trial data than in the postmarketing reports, particularly in association with Gardasil and certain meningococcal vaccines (abbreviated as MenACWY). These events include alcohol intoxication and drug overdose; suicidal thoughts or attempts; head and limb injuries; and falls resulting in injuries. Noting that syncope (fainting) is a common post-vaccination reaction in adolescents and young adults, the CDC states, “In 2005, the Vaccine Adverse Event Reporting System (VAERS) began detecting a trend of increasing syncope reports that coincided with the licensure of 3 vaccines for adolescents: human papillomavirus (HPV), MenACWY, and Tdap. Of particular concern among adolescents has been the risk for serious secondary injuries, including skull fracture and cerebral hemorrhage.” (One of the robustly healthy volunteers in the current clinical trials for the Moderna Covid-19 vaccine illustrated this very point, narrowly escaping injury when his girlfriend caught him in the midst of a fainting episode.)
• Illustrating how vaccines can cause what they are supposed to prevent, the clinical trials for the ProQuad measles-mumps-rubella-varicella vaccine—intended to prevent infections associated with rashes—highlighted an astounding array of rashes. The ProQuad insert lists seven different types of rash-related adverse reactions: “rash,” “injection-site rash,” “measles-like rash,” “rubella-like rash,” “varicella-like rash,” “vesicular rash” and “viral exanthema” (an eruptive rash associated with viral infections). Across both the clinical trial and postmarketing data, ProQuad injection also appears to precede numerous infections, including “atypical measles” and measles, varicella (chickenpox), bronchitis, cellulitis and other skin infections, herpes simplex (cold sores), herpes zoster (shingles), influenza or “influenza-like illness,” meningitis, pneumonia, respiratory tract infections, sinusitis, sore throats and other viral infections.

Researchers interested in solutions rather than convenient coronavirus cover stories would do well to review the information contained in vaccine package inserts.

Mysteries explained?

One of the autoimmune conditions encountered during the clinical trials for meningococcal and rotavirus vaccines (and also reported post-licensure) is a condition called Kawasaki disease (KD). Diagnosed solely on the basis of symptoms (high fever plus symptoms such as rash, redness and lymph node swelling), KD came out of nowhere in the 1960s and 1970s when childhood vaccine programs were starting to gear up. The published literature confirms Bexero meningococcal B and rotavirus vaccination as likely triggers for KD and, in addition, points to numerous other vaccines as possible culprits, including those for hepatitis A, hepatitis B, influenza, Prevnar-13 and multiple vaccines administered in a single health care visit. Canadian researchers have identified KD as a “condition of interest” for pediatric vaccine safety surveillance.

Ordinarily fairly obscure, KD made headlines this year when researchers started speculating that it might be one of the apparently myriad faces of SARS-CoV-2. In the UK—the first country in the world to start administering (in 2015) three doses of Bexero to infants—researchers were also the first to suggest that KD might be Covid-19-related. This week, a different group of researchers raised the same question about another low-profile autoimmune condition, myasthenia gravis, asking whether it, too, could be connected to SARS-CoV-2. Researchers interested in solutions rather than convenient coronavirus cover stories would do well to review the information contained in vaccine package inserts. This information clearly points the way to a different set of questions and answers, pertaining not only to autoimmunity but also to the many other health problems besieging American children.

Table 1. Vaccine package inserts reviewed

Type of Vaccine	Brand Name	Manufacturer
Vaccines containing diphtheria, tetanus and pertussis components	Adacel (Tdap)	Sanofi Pasteur
Boostrix (Tdap)	GlaxoSmithKline (GSK)
Daptacel (DTaP)	Sanofi
Diphtheria and Tetanus Toxoids Adsorbed (DT)	Sanofi
Infanrix (DTaP)	GSK
Kinrix (DTaP-IPV)	GSK
Pediarix (DTaP-HepB-IPV)	GSK
Pentacel (DTaP-IPV/Hib)	Sanofi
Quadracel (DTaP-IPV)	Sanofi
Tdvax (Td)	MassBiologics
Tenivac (Td)	Sanofi
Haemophilus influenzae type b (Hib)	ActHIB	Sanofi
Hiberix	GSK
PedvaxHIB	Merck
Hepatitis A and/or B	Engerix-B (HepB)	GSK
Havrix (HepA)	GSK
Recombivax HB (HepB)	Merck
Twinrix (HepA/HepB)	GSK
Vaqta (HepA)	Merck
Human papillomavirus (HPV)	Gardasil	Merck
Gardasil 9	Merck
Influenza	Afluria Quadrivalent	Sequirus
Fluarix	GSK
Flublok Quadrivalent (age 18 and older)	Protein Sciences Corporation
Flucelvax	Sequirus
Flulaval Quadrivalent	GSK
FluMist	AstraZeneca
Fluzone Quadrivalent	Sanofi
Meningococcal A, C, W and/or Y	Menactra	Sanofi
Menomune	Sanofi
Menveo	GSK
Meningococcal B	Bexero	GSK
Trumenba	Pfizer
Measles-mumps-rubella (MMR) and MMR+varicella (MMRV)	MMR-II	Merck
Proquad	Merck
Pneumococcal	Prevnar-13	Pfizer
Pneumovax-23	Merck
Inactivated polio (IPV)	IPOL	Sanofi
Rotavirus vaccines	Rotarix	GSK
RotaTeq	Merck
Varicella	Varivax	Merck

Table 2. Clinical trial and post-marketing adverse events reported in vaccine package inserts, by body system

Body System	Medical Disorder	Reported in Clinical Trials	Reported Post-marketing
Allergic (6)	Allergic reactions/ hypersensitivity	Varivax	ActHIB, Adacel, Afluria, Bexero, Boostrix, Daptacel, Engerix-B, Fluarix, Flublok, FluMist, Fluzone, Gardasil/Gardasil 9, Hiberix, Infanrix, IPOL, Kinrix, Menveo, Pediarix, Pentacel, Quadracel, Recombivax, Tenivac, Trumenba, Twinrix
Allergy to vaccine	Gardasil/Gardasil 9
Anaphylaxis and anaphylactoid reactions, including shock	Bexero, Fluarix, MMR-II	ActHIB, Adacel, Afluria, Bexero, Boostrix, Daptacel, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Havrix, Hiberix, Infanrix, IPOL, Kinrix, Menactra, Menveo, MMR-II, Pediarix, Pentacel, Pneumovax-23, Prevnar-13, ProQuad, Quadracel, Recombivax, RotaTeq, Tenivac, Trumenba, Twinrix, Varivax
Angioedema, angioneurotic edema	Menveo, MMR-II, Recombivax	ActHIB, Adacel, Boostrix, Daptacel, Engerix-B, Fluarix, Flucelvax, Flulaval, FluMist, Fluzone, Havrix, Hiberix, Infanrix, Kinrix, Menactra, Menomune, MMR-II, Pediarix, PedvaxHIB, Pneumovax-23, Prevnar-13, ProQuad, RotaTeq, Tenivac, Twinrix, Varivax
Serum sickness		Afluria, Engerix-B, Fluarix, Havrix, Pneumovax-23, Recombivax, Twinrix
Urticaria [hives]	Engerix-B, Havrix, MMR-II, PedVaxHIB, Prevnar-13, Recombivax, Twinrix, Vaqta, Varivax	ActHIB, Adacel, Afluria, Boostrix, DT, Engerix-B, Fluarix, Flucelvax, Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Hiberix, Infanrix, IPOL, Kinrix, Menactra, MMR-II, Pediarix, Pentacel, Pneumovax-23, Prevnar-13, Quadracel, Recombivax, RotaTeq, Tenivac, Twinrix
Autoimmune (15)	Autoimmune diseases		Gardasil/Gardasil 9
Autoimmune thyroiditis	Gardasil/Gardasil 9
Celiac disease	Gardasil/Gardasil 9
Cutaneous lupus erythematosus	Gardasil/Gardasil 9
Diabetes mellitus (insulin-dependent)	Boostrix, Gardasil/Gardasil 9, Pediarix, Pneumovax-23	MMR-II
Graves’/Basedow’s disease	Gardasil/Gardasil 9
Guillain-Barré syndrome (GBS)	IPOL, MMR-II, PedVaxHIB	Adacel, Afluria, Engerix-B, Fluarix, Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Havrix, Menactra, Menomune, MMR-II, PedvaxHIB, Pneumovax-23, ProQuad, Recombivax, Tenivac, Vaqta, Varivax
Kawasaki disease	Menveo, Rotarix, RotaTeq	Rotarix, RotaTeq
Lupus-like syndrome		Recombivax
Multiple sclerosis (or exacerbation)	Gardasil/Gardasil 9	Engerix-B, Havrix, Recombivax, Twinrix
Pancreatitis	MMR-II, Pneumovax-23	Gardasil/Gardasil 9, MMR-II
Rheumatoid arthritis/juvenile rheumatoid arthritis	Gardasil/Gardasil 9
Scleroderma	Gardasil/Gardasil 9
Systemic lupus erythematosus	Gardasil/Gardasil 9	Recombivax
Thrombocytopenia/idiopathic thrombocytopenic purpura (ITP) [low platelets]	Daptacel, Gardasil/Gardasil 9, MMR-II, PedVaxHIB	Afluria, Engerix-B, Fluzone, Gardasil/Gardasil 9, Havrix, Infanrix, Kinrix, MMR-II, Pneumovax-23, ProQuad, Recombivax, Rotarix, Twinrix, Vaqta, Varivax
Blood/lymphatic system (11)	Anemia (aplasic or hemolytic)		Gardasil/Gardasil 9, Pneumovax-23, ProQuad, Varivax
Epistaxis [nosebleed]		FluMist, ProQuad
Extravasation [blood vessel leakage]		ProQuad
Hematochezia [bloody stools]	RotaTeq	ProQuad, Rotarix, RotaTeq
Hemorrhage	Gardasil/Gardasil 9
Increased erythrocyte sedimentation rate		Recombivax
Leukocytosis [increased white blood cells]	MMR-II	MMR-II, Pneumovax-23
Lymphadenitis/swollen lymph nodes	Adacel	Boostrix, Pneumovax-23, ProQuad
Lymphadenopathy, including regional	Engerix-B, Havrix, MMR-II, Recombivax, Varivax	Boostrix, Daptacel, DT, Fluarix, Flulaval, Fluzone, Gardasil/Gardasil 9, Infanrix, IPOL, Kinrix, Menactra, Menveo, MMR-II, PedvaxHIB, Pneumovax-23, Prevnar-13, ProQuad, Tenivac
Neutropenia, chronic	Pediarix
Thrombocytopenia/idiopathic thrombocytopenic purpura (ITP) [low platelets]*	Daptacel, Gardasil/Gardasil 9, MMR-II, PedVaxHIB	Afluria, Engerix-B, Fluzone, Gardasil/Gardasil 9, Havrix, Infanrix, Kinrix, MMR-II, Pneumovax-23, ProQuad, Recombivax, Rotarix, Twinrix, Vaqta, Varivax
Cardiac (10)	Angina pectoris	Pneumovax-23, Tenivac
Cyanosis* [bluish, low oxygen]		Daptacel, Hiberix, Infanrix, Pediarix, Pentacel, Prevnar-13, Quadracel
Heart failure	Pneumovax-23
Hypotension	Engerix-B, Recombivax	Adacel, Menactra
Myocardial infarction	Pneumovax-23
Myocarditis [heart muscle inflammation]	Gardasil/Gardasil 9	Adacel, Boostrix
Palpitations		Engerix-B, Twinrix
Pericarditis [pericardial inflammation]		FluMist
Pleuropericarditis	Flublok (> age 50)
Tachycardia [abnormally high heart rate]		Engerix-B, Fluarix, Recombivax, Twinrix
Congenital (1)	Congenital anomaly		Havrix
Death, by cause (40)	Unspecified	Flublok, IPOL, Prevnar-13, Tenivac	Gardasil/Gardasil 9
Acute lymphocytic leukemia	Gardasil/Gardasil 9
Acute renal failure	Gardasil/Gardasil 9
Arrhythmia	Gardasil/Gardasil 9
Asphyxia	Pentacel
Aspiration	Daptacel
Autoimmune disease	Gardasil/Gardasil 9
Breast cancer	Gardasil/Gardasil 9
Cardiopulmonary arrest	Tenivac
Cardiovascular	Prevnar-13, Pneumovax-23
Cerebral hemorrhage	Gardasil/Gardasil 9
Cerebrovascular accident	Gardasil/Gardasil 9
Congenital immunodeficiency and sepsis	Pediarix
Convulsive disorder	Pediarix
Drug overdose	Gardasil/Gardasil 9
Fetal		MMR-II
Gunshot wound	Gardasil/Gardasil 9
Head trauma	Pentacel
Homicide	Gardasil/Gardasil 9
Hyperthyroidism	Gardasil/Gardasil 9
Hypovolemic septic shock	Gardasil/Gardasil 9
Infectious disease	Gardasil/Gardasil 9
Intussusception	RotaTeq	Rotarix, RotaTeq
Motor vehicle accident	Gardasil/Gardasil 9
Myocardial infarction	Tenivac
Nasopharyngeal cancer	Gardasil/Gardasil 9
Neoplasm	Gardasil/Gardasil 9, Prevnar-13
Neuroblastoma	Pediarix, Pentacel
Pancreatic cancer	Gardasil/Gardasil 9
Peritonitis	Prevnar-13
Pneumonia	Rotarix
Pulmonary embolism	Gardasil/Gardasil 9
Pulmonary infection	Prevnar-13
Pulmonary tuberculosis	Gardasil/Gardasil 9
Sepsis, septic shock	Gardasil/Gardasil 9, Menveo, Prevnar-13
Stomach adenocarcinoma	Gardasil/Gardasil 9
Sudden infant death syndrome (SIDS)	Menveo, Pediarix, Pentacel, Prevnar-13, RotaTeq	Infanrix
Suicide	Gardasil/Gardasil 9
Traumatic brain injury/cardiac arrest	Gardasil/Gardasil 9
Unexplained sudden death	Gardasil/Gardasil 9
Ear/labyrinth (8)	Earache	Recombivax
Ear pain		Engerix-B, Infanrix, Menveo, ProQuad, Twinrix
Hearing impaired		Menveo
Nerve deafness	MMR-II	MMR-II, ProQuad
Otitis media/ear infection	Afluria, Fluarix, PedVaxHIB, RotaTeq, Vaqta, Varivax	MMR-II
Tinnitis		Engerix-B, Recombivax, Twinrix
Vertigo	Havrix, Recombivax, Twinrix	Engerix-B, Fluarix, Menveo
Vestibular/balance disorder		Menveo
Endocrine (6)	Cushing’s syndrome	Menveo
Goiter	Gardasil/Gardasil 9
Hyperthyroidism	Gardasil/Gardasil 9
Hypothyroidism	Gardasil/Gardasil 9
Thyroiditis	Gardasil/Gardasil 9
Toxic nodular goiter	Gardasil/Gardasil 9
Eye (17)	Conjunctivitis	Vaqta
Eye complaints	Varivax
Eye irritation/itching	Vaqta
Eye pain		Fluarix, Flulaval
Eye redness		Fluarix
Eye swelling		Bexero, Fluarix
Eyelid ptosis [drooping]		Menveo
Eyelid swelling		Fluarix, ProQuad
Keratitis [corneal inflammation]		Engerix-B
Ocular hyperemia [eye inflammation]		Fluzone
Ocular palsies [nerve damage]	MMR-II	MMR-II, ProQuad
Optic neuritis/neuropathy, papillitis [optic nerve inflammation]	Gardasil/Gardasil 9, MMR-II	Engerix-B, Fluzone, MMR-II, ProQuad, Recombivax, Twinrix
Photophobia [light intolerance]	Havrix	Flulaval
Retinitis, necrotizing [inflammation]	MMR-II	MMR-II, ProQuad, Varivax
Retrobulbar neuritis [nerve damage]		MMR-II, ProQuad
Uveitis [eye inflammation]	Gardasil/Gardasil 9	Recombivax
Visual disturbances		Engerix-B, Recombivax, Twinrix
Gastrointestinal (21)	Abdominal pain, discomfort	Boostrix, Engerix-B, Fluarix, Flulaval, FluMist, Gardasil/Gardasil 9, Havrix, Menomune, Recombivax, Twinrix, Vaqta, Varivax	Fluarix, ProQuad
Candidiasis		ProQuad
Colonic polyp	Tenivac
Constipation	Engerix-B, Infanrix, Vaqta, Varivax	Recombivax
Crohn’s disease	Gardasil/Gardasil 9
Diarrhea	Adacel, Afluria, Boostrix, Engerix-B, Fluarix, Flulaval, Gardasil/Gardasil 9, Havrix, Hiberix, Menactra, Menomune, Menveo, MMR-II, PedVaxHIB, Prevnar-13, ProQuad, Recombivax, Rotarix, RotaTeq, Trumenba, Twinrix, Vaqta, Varivax	Daptacel, FluMist, Menomune, MMR-II, Pediarix, Pentacel
Dysgeusia [altered sense of taste]	Havrix
Dyspepsia [indigestion]	Pneumovax-23, Recombivax	Engerix-B, Twinrix
Dysphagia [swallowing difficulties]		Flulaval
Gastroenteritis	Flulaval, Gardasil/Gardasil 9, Kinrix, Menveo, Pediarix, Pentacel, Prevnar-13, Rotarix, RotaTeq, Vaqta	Rotarix, RotaTeq
Gastrointestinal infection	FluMist
Inflammatory bowel disease	Gardasil/Gardasil 9
Inguinal hernia	Menactra
Intussusception, including recurrent	Rotarix, RotaTeq	Rotarix, RotaTeq
Mouth ulcers		ProQuad
Nausea	Adacel, Afluria, Bexero, Boostrix, Engerix-B, Fluarix, Flublok, Flulaval, Gardasil/Gardasil 9, Havrix, Menveo, MMR-II, Recombivax, Twinrix, Vaqta, Varivax	Daptacel, DT, Fluarix, FluMist, Gardasil/Gardasil 9, Menomune, MMR-II, Pneumovax-23, Tdvax
Swelling of mouth, throat or tongue		Fluarix
Teething	Afluria, Vaqta, Varivax
Ulcerative colitis	Gardasil/Gardasil 9, Pneumovax-23
Vitello-intestinal duct remnant	Menveo
Vomiting	ActHIB, Adacel, Afluria, Boostrix, Daptacel, Engerix-B, Fluarix, Flulaval, Fluzone, Gardasil/Gardasil 9, Havrix, Hiberix, IPOL, Menactra, Menomune, Menveo, MMR-II, PedVaxHIB, Prevnar-13, ProQuad, Recombivax, Rotarix, RotaTeq, Trumenba, Twinrix, Vaqta, Varivax	Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Menomune, MMR-II, Pediarix, Pentacel, Pneumovax-23, Tenivac
General and injection site (35)	Abnormal gait		Flulaval
Apathy		ProQuad
Asthenia [fatigue, weakness]	Hiberix, Pneumovax-23, Vaqta	Fluarix, Flulaval, Fluzone, Gardasil/Gardasil 9, Infanrix, Menomune, Pediarix, Tenivac
Body aches	Adacel, Recombivax	Fluarix
Chest pain	Pneumovax-23, Tenivac	Fluarix, Flulaval, Fluzone
Chills/shivering	Adacel, Afluria, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, FluMist, Menactra, , Menveo, Prevnar-13, Recombivax, Trumenba, Vaqta, Varivax	Fluarix, Gardasil/Gardasil 9, Havrix, Menomune, Twinrix
Decreased limb mobility		Pneumovax-23
Dehydration	Kinrix, Menveo, Pentacel, Rotarix, Vaqta
Drowsiness/sleepiness	ActHIB, Daptacel, Fluarix, Flulaval, Fluzone, Havrix, Hiberix, Infanrix, IPOL, Kinrix, Menactra, Menomune, Menveo, Pediarix, PedvaxHIB
Ecchymosis [bruising]	Engerix-B, Fluarix, Flucelvax, Pneumovax-23, ProQuad, Recombivax, Twinrix, Vaqta	Engerix-B, Recombivax, Twinrix
Edema	Vaqta	Adacel
Fatigue	Afluria, Bexero, Boostrix, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, Havrix, Menactra, Menomune, Menveo, MMR-II, Prevnar-13, Recombivax, Trumenba, Twinrix, Varivax	Gardasil/Gardasil 9, Menomune, Menveo
Feeling hot		Fluarix
Fever/pyrexia	ActHIB, Adacel, Afluria, Bexero, Boostrix, Daptacel, DT, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Havrix, Hiberix, Infanrix, IPOL, Kinrix, Menactra, Menomune, Menveo, MMR-II, Pediarix, PedVaxHIB, Pentacel, Prevnar-13, ProQuad, Quadracel, Recombivax, Rotarix, RotaTeq, Tenivac, Trumenba, Twinrix, Vaqta, Varivax	Menomune, Menveo, MMR-II, Pneumovax-23, Tdvax
Hematoma	Gardasil/Gardasil 9, Havrix, Varivax
Hypernatremia [excess sodium]	Kinrix
Increased arm circumference	Adacel, Boostrix, Daptacel, Infanrix, Kinrix, Pentacel, Quadracel
Increased thigh circumference	Infanrix
Injected limb—extensive swelling	Boostrix, Daptacel, Infanrix, Quadracel	ActHIB, Bexero, Hiberix, Menactra, Menveo
Injection-site abscess		Adacel, Daptacel, Fluarix, Flulaval, PedvaxHIB, Pentacel, Quadracel
Injection-site bruising	Afluria, Gardasil/Gardasil 9, ProQuad, Vaqta	Adacel, Flulaval
Injection-site cellulitis		Afluria, Daptacel, Fluarix, Flulaval, Menveo, Pediarix, Quadracel, Tenivac
Injection-site pain and other reactions (induration, warmth)	ActHIB, Adacel, Afluria, Bexero, Boostrix, Daptacel, DT, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, Fluzone, Gardasil/Gardasil 9, Havrix, Hiberix, Infanrix, IPOL, Kinrix, Menactra, Menomune, Menveo, Pediarix, PedvaxHIB, Pentacel, Pneumovax-23, Prevnar-13, ProQuad, Quadracel, Recombivax, Tenivac, Trumenba, Twinrix, Vaqta, Varivax	Adacel, Afluria, Bexero, Boostrix, Daptacel, DT, Engerix-B, Fluarix, Flucelvax, Flulaval, Havrix, Hiberix, Infanrix, IPOL, Kinrix, Menactra, Menomune, Menveo, MMR-II, Pediarix, Pentacel, Pneumovax-23, Prevnar-13, ProQuad, Quadracel, Tdvax, Tenivac, Twinrix
Injection-site rash	ProQuad, Vaqta, Varivax	Daptacel, Flulaval, IPOL, Prevnar-13
Interference with normal activity of arm	Daptacel, DT, Prevnar-13
Itching	Afluria, Varivax
Lightheadedness	Recombivax
Listlessness		Quadracel
Malaise	Adacel, Afluria, Engerix-B, Fluarix, Flucelvax, Fluzone, Gardasil/Gardasil 9, Havrix, Menactra, Menomune, Menveo, MMR-II, Quadracel, Recombivax, Tenivac, Varivax	Gardasil/Gardasil 9, Menomune, Menveo, MMR-II, Pneumovax-23, Tdvax, Twinrix
Medical attention sought	Pediarix
Pain in extremity	Fluarix
Peripheral edema		ActHIB, MMR-II, Pneumovax-23, ProQuad, Tdvax, Tenivac, Varivax
Severe pain	Bexero
Swelling	Afluria, Adacel, Boostrix, Daptacel, DT, Engerix-B, Fluarix, Flublok, Flucelvax, Fluzone, Infanrix, IPOL, Kinrix, Menactra, Menomune, Pediarix, PedVaxHIB, Pentacel, Pneumovax-23, Prevnar-13, ProQuad, Quadracel, Recombivax, Tenivac, Trumenba, Twinrix, Vaqta, Varivax	Menveo, MMR-II, ProQuad
Tiredness	Adacel, FluMist, IPOL
Hepatobiliary/liver (3)	Elevation of liver enzymes		Recombivax
Hepatitis	Menveo	Havrix, Twinrix
Jaundice		Havrix, Twinrix
Infections and infestations (51)	Appendicitis	Gardasil/Gardasil 9, Menveo
Atypical measles	MMR-II	MMR-II, ProQuad
Bronchiolitis	Daptacel, Pediarix, Pentacel, Prevnar-13, RotaTeq
Bronchitis	Flulaval	Infanrix, ProQuad
Cellulitis	Daptacel, Infanrix, Tenivac, Vaqta	Daptacel, Gardasil/Gardasil 9, Infanrix, Pneumovax-23, ProQuad, Tdvax, Varivax
Cellulitis-like reaction	Afluria
Chlamydia	Gardasil/Gardasil 9
Cholecystitis	Tenivac
Croup	Afluria, Fluzone, Vaqta
Early-onset Hib disease	PedVaxHIB	PedvaxHIB
Glomerulonephritis	Gardasil/Gardasil 9
Herpes simplex/cold sore	Varivax	ProQuad
Herpes zoster [shingles]	ProQuad, Menactra	Engerix-B, ProQuad, Recombivax, Twinrix, Varivax
Infection		ProQuad
Influenza, influenza-like illness	Engerix-B, Fluarix, Gardasil/Gardasil 9, Recombivax, Twinrix	Afluria, Flulaval,Havrix, ProQuad
Invasive Hib disease		Pentacel
Laryngitis	Menveo	Flulaval
Laryngotracheo-bronchitis	Vaqta
Localized infection	Tenivac
Measles		ProQuad
Measles-like rash	MMR-II, ProQuad, Vaqta	MMR-II
Meningitis (aseptic, eosinophilic)	Daptacel	Engerix-B, FluMist, MMR-II, Pentacel, ProQuad, Twinrix, Varivax
Nasal congestion	Afluria, Fluarix, Gardasil/Gardasil 9, Vaqta
Pelvic inflammatory disease	Gardasil/Gardasil 9, Menveo
Pharyngitis/ nasopharyngitis	Afluria, Bexero, Fluarix, Flulaval, Gardasil/Gardasil 9, Havrix, Pneumovax-23, ProQuad, Recombivax, RotaTeq, Vaqta	Fluarix, Varivax
Pharyngitis streptococcal	Vaqta
Pharyngolaryngeal pain	Fluarix
Pneumonia, pneumonitis, lobar pneumonia, bilateral pneumonia	Daptacel, Gardasil/Gardasil 9, Hiberix, Menomune, Menveo, MMR-II, Pentacel, Prevnar-13, RotaTeq, Varivax	MMR-II, ProQuad, Varivax
Pulmonary congestion		ProQuad
Pulmonary embolism	Gardasil/Gardasil 9	Gardasil/Gardasil 9
Nephritis/pyelonephritis [kidney infection]	Gardasil/Gardasil 9
Pertussis	Daptacel
Respiratory congestion	Fluarix, Vaqta
Respiratory tract infection (upper or lower)	Afluria, Engerix-B, Fluarix, Flulaval, FluMist, Gardasil/Gardasil 9, Havrix, PedVaxHIB, Pneumovax-23, ProQuad, Recombivax, Twinrix, Vaqta, Varivax	Infanrix, Pediarix, ProQuad
Rhinitis	Fluarix, Flucelvax, MMR-II, Recombivax, Vaqta	Fluarix, Flulaval, Havrix, MMR-II, Pentacel, ProQuad
Roseola	Vaqta
Rubella-like rash	ProQuad, Vaqta
Secondary bacterial infection (skin, tissue)		Varivax
Sepsis	Daptacel, Pediarix
Sinusitis	FluMist	ProQuad
Skin infection		ProQuad
Sore throat	FluMist, MMR-II	MMR-II, ProQuad
Sneezing	FluMist
Staph infection	Menveo
Tonsillitis		Fluarix
Tracheitis	PedVaxHIB
Transmission of vaccine virus strains		RotaTeq
Varicella	Flulaval, Menveo
Varicella (vaccine strain)		ProQuad, Varivax
Varicella-like rash	ProQuad, Vaqta, Varivax	ProQuad
Viral infection	ProQuad, Vaqta	Pentacel
Injury (intentional and  unintentional) (10)	Accidental drug ingestion	Hiberix
Alcohol intoxication	Pneumovax-23
Fall	Menactra	Menveo
Falling with injury		Gardasil/Gardasil 9
Head injury		Menveo
Intentional multiple-drug overdose	Menveo
Limb injury	Menveo
Road accident	Menveo
Suicidal depression	Menveo
Suicide attempt	Menveo
Investigations (6)	Abnormal liver function tests		Engerix-B, Twinrix
Alanine aminotransferase increased		Menveo
Body temperature increased		Menveo
Creatine phosphokinase increased	Havrix
Diagnostic studies	Pediarix
Increased serum C-reactive protein		Pneumovax-23
Metabolic (3)	Change in eating habits	Menveo
Loss of appetite, decreased appetite	Afluria, DT, Fluarix, Flulaval, FluMist, Fluzone, Havrix, Hiberix, Infanrix, Kinrix, Menactra, Pediarix, Prevnar-13, Recombivax, Rotarix, Varivax	Pentacel
Mitochondrial encephalomyopathy, Leigh syndrome exacerbation [neurometabolic]		FluMist
Musculoskeletal and connective tissue (24)	Ankylosing spondylitis [rare arthritis]	Gardasil/Gardasil 9
Arm pain	Engerix-B, Vaqta
Arthralgia [joint pain]	Adacel, Bexero, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, Gardasil/Gardasil 9, Havrix, MMR-II, Menactra, Menomune, Menveo, Prevnar-13, Recombivax, Tenivac, Trumenba, Twinrix, Varivax	Boostrix, Engerix-B, Gardasil/Gardasil 9, IPOL, Menomune, Menveo, MMR-II, Pneumovax-23, ProQuad, Recombivax, Tdvax, Twinrix
Arthritis	Gardasil/Gardasil 9, MMR-II	Engerix-B, Flulaval, MMR-II, Pneumovax-23, ProQuad, Recombivax, Twinrix
Arthropathy	Gardasil/Gardasil 9
Back pain	Engerix-B, Fluarix, Gardasil/Gardasil 9, Pneumovax-23, Recombivax, Twinrix, Vaqta	Boostrix
Bone pain		Menveo
Cramps	Engerix-B, Recombivax
Hip and wrist fracture	Tenivac
Hypotonia [low muscle tone]	Pentacel	Daptacel, Hiberix, Infanrix, Pediarix, Prevnar-13, Quadracel
Invertebral disc protrusion	Menactra
Muscle spasm		Adacel
Muscle weakness/weakness	Adacel, Engerix-B, Recombivax, Tenivac, Twinrix	Engerix-B, Flulaval, Recombivax, Twinrix
Musculoskeletal pain	Fluarix	ProQuad
Musculoskeletal stiffness		Havrix
Myalgia [muscle pain]	Adacel, Afluria, Bexero, Daptacel, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Havrix, Menactra, Menveo, MMR-II, Pneumovax-23, Quadracel, Recombivax, Trumenba, Twinrix, Vaqta, Varivax	Boostrix, Gardasil/Gardasil 9, IPOL, Menactra, Menomune, MMR-II, ProQuad, Tdvax, Tenivac
Myositis [muscle inflammation]		Adacel
Neck pain	Engerix-B, Fluarix, Pneumovax-23, Recombivax
Pain in extremities		Fluarix, Fluzone, Pediarix, Recombivax, Tdvax, Tenivac
Psoriatic arthropathy	Gardasil/Gardasil 9
Reactive arthritis	Gardasil/Gardasil 9
Shoulder pain	Engerix-B, Recombivax
Stiff neck	Recombivax, Varivax
Stiffness	Pneumovax-23, Vaqta, Varivax
Nervous system (45)	Acute disseminated encephalomyelitis (ADEM)	Menveo, MMR-II	Gardasil/Gardasil 9, Menactra, MMR-II, ProQuad
Ataxia [nervous system dysfunction]	MMR-II	MMR-II, ProQuad, Varivax
Bulging fontanelle		Pediarix
Cerebellar ataxia		Vaqta
Convulsions/seizures	ActHIB, Daptacel, Havrix, Hiberix, Infanrix, Menactra, Menomune, Menveo, Pediarix, PedVaxHIB, Pentacel, Prevnar-13, RotaTeq	ActHIB, Adacel, Afluria, Boostrix, Daptacel, DT, Fluarix, Flulaval, Fluzone, Gardasil/Gardasil 9, Havrix, Hiberix, IPOL, Kinrix, Menactra, MMR-II, Quadracel, Recombivax, Tdvax, Twinrix, Varivax
Depressed level of consciousness		Boostrix, Pediarix, Pentacel
Dizziness	Engerix-B, Gardasil/Gardasil 9, MMR-II, Recombivax, Twinrix	Fluarix, Flulaval, Fluzone, Gardasil/Gardasil 9, Havrix, Menactra, Menomune, Menveo, MMR-II, ProQuad, Tdvax, Tenivac, Varivax
Encephalitis, vaccine-induced encephalitis [brain inflammation]	MMR-II	Boostrix, Engerix-B, FluMist, MMR-II, Pediarix, Recombivax, Twinrix, Vaqta, Varivax
Encephalomyelitis [brain and spinal cord]		Afluria, Fluarix, Fluzone
Encephalopathy [brain disease]	MMR-II, Pentacel	Afluria, Engerix-B, Flulaval, Havrix, Infanrix, MMR-II, ProQuad, Twinrix
Facial palsy, Bell’s palsy		Adacel, Boostrix, Engerix-B, Fluarix, FluMist, Fluzone, Menactra, Menveo, ProQuad, Recombivax, Twinrix, Varivax
Facial (or cranial) nerve paralysis	Adacel	Flulaval
Facial paresis [impaired facial movement]		Fluarix, Menveo
Febrile convulsions/seizures	Afluria, Daptacel, Fluzone, Infanrix, Hiberix, Menveo, MMR-II, Pediarix, Pentacel, Prevnar-13, ProQuad, RotaTeq, Vaqta, Varivax	Afluria, Daptacel, Fluzone, IPOL, MMR-II, PedvaxHIB, Pneumovax-23, ProQuad, Quadracel, Recombivax
Headache	Adacel, Afluria, Bexero, Boostrix, Engerix-B, Fluarix, Flublok, Flucelvax, Flulaval, FluMist, Fluzone, Gardasil/Gardasil 9, Havrix, Menactra, Menomune, Menveo, Pneumovax-23, Prevnar-13, ProQuad, Quadracel, Recombivax, Tenivac, Trumenba, Twinrix, Vaqta, Varivax	DT, Gardasil/Gardasil 9, Infanrix, IPOL, Menomune, Menveo, MMR-II, ProQuad, Tdvax, Twinrix
Hypoesthesia [decreased tactile sensitivity]		Adacel, Engerix-B, Fluarix, Flulaval, Havrix, Recombivax, Twinrix
Hypokinesia [loss of muscle movement]		Flulaval
Hypotonic-hyporesponsive episode (HHE)	Daptacel, Infanrix, Prevnar-13	Daptacel, Hiberix, Kinrix, Pediarix, Pentacel, Quadracel
Hypertonia	Havrix
Infantile spasms	Daptacel, Pediarix
Lethargy	ActHIB, Daptacel, FluMist, Pentacel	Pediarix
Limb paralysis		Flulaval
Measles inclusion body encephalitis (MIBE)	MMR-II	MMR-II, ProQuad
Migraine	Adacel, Fluarix, Twinrix	Engerix-B, Recombivax
Motor neuron disease		Gardasil/Gardasil 9
Myelitis [spinal cord disease]		Adacel, Fluarix, Fluzone, Havrix, Recombivax, Twinrix
Nerve compression	Adacel
Neuralgia [nerve pain]		Afluria
Neuritis (including brachial, polyneuritis)	MMR-II	Adacel, Afluria, Engerix-B, Fluarix, Fluzone, MMR-II, Twinrix
Neuropathy, polyneuropathy	MMR-II	Afluria, Engerix-B, Fluarix, Havrix, MMR-II, ProQuad, Recombivax, Twinrix
Numbness	Varivax
Paralysis		Engerix-B, Gardasil/Gardasil 9, Twinrix
Paresis [partial paralysis]		Engerix-B, Twinrix
Paresthesia [abnormal skin sensations]	MMR-II, Recombivax, Twinrix	Adacel, Afluria, Boostrix, Engerix-B, Fluarix, Flucelvax, Flulaval, Fluzone, Havrix, IPOL, Menactra, Menomune, MMR-II, Pneumovax-23, ProQuad, Tenivac, Varivax
Partial seizures, seizures	Menveo	Daptacel, Engerix-B, ProQuad
Presyncope [feeling faint]		Flucelvax
Radiculopathy [“pinched nerve” in spine]	Pneumovax-23	Pneumovax-23, Recombivax
Somnolence	Engerix-B, ProQuad, Twinrix	Daptacel, DT, Flulaval, Havrix, Hiberix, IPOL, Pediarix, Pentacel, Quadracel, Recombivax
Subacute sclerosing panencephalitis (SSPE)	MMR-II	MMR-II, ProQuad
Syncope, vasovagal syncope [fainting]	Flublok, MMR-II, Twinrix	Adacel, Bexero, Boostrix, Daptacel, DT, Engerix-B, Fluarix, Flucelvax, Flulaval, Fluzone, Gardasil/Gardasil 9, Havrix, Hiberix, Infanrix, Kinrix, Menactra, Menomune, Menveo, MMR-II, Pediarix, ProQuad, Recombivax, Tenivac, Trumenba
Tingling	Engerix-B
Tonic convulsions	Menveo	Menveo
Transverse myelitis	MMR-II	Afluria, Engerix-B, Fluzone, Gardasil/Gardasil 9, Menactra, MMR-II, ProQuad, Recombivax, Twinrix, Varivax
Tremors	Pneumovax-23	Flulaval, ProQuad
Unresponsiveness	Daptacel
Psychiatric (15)	Agitation	Engerix-B, Twinrix	IPOL, ProQuad, Recombivax
Anorexia	ActHIB, Daptacel, Havrix, Engerix-B, IPOL, Menactra, Menomune, Twinrix, Vaqta
Crying (abnormal, unusual, persistent or inconsolable)	ActHIB, Daptacel, DT, Flulaval, Fluzone, Hiberix, Infanrix, IPOL, Menactra, Menveo, PedVaxHIB, Pentacel, Prevnar-13, Vaqta	Pediarix
Decreased sleep	Prevnar-13
Depression	Pneumovax-23
Disturbed sleep	Recombivax, Varivax
Fretfulness	Daptacel
Fussiness	ActHIB, Daptacel, Hiberix, Infanrix, IPOL, Pediarix, Pentacel
Hypersomnia		ProQuad
Increased sleep	Prevnar-13
Insomnia	Engerix-B, Gardasil/Gardasil 9, Havrix, Recombivax, Twinrix, Vaqta	Flulaval, Pediarix
Irritability	ActHIB, Afluria, , Engerix-B, Fluarix, Flulaval, FluMist, Fluzone, Havrix, Hiberix, Infanrix, IPOL, Menactra, Menomune, Menveo, Pediarix, PedVaxHIB, Pentacel, Prevnar-13, ProQuad, Recombivax, Rotarix, RotaTeq, Twinrix, Vaqta, Varivax	MMR-II, Recombivax
Nervousness	Varivax	Pediarix, ProQuad
Restlessness	Hiberix	Pediarix
Screaming		Daptacel, Pediarix, Pentacel, Quadracel
Reproductive (2)	Dysmenorrhea	Fluarix
Menstruation disorders	Vaqta
Respiratory, thoracic and mediastinal (19)	Apnea	ActHIB, Daptacel	Engerix-B, Hiberix, Infanrix, Kinrix, Pediarix, Pentacel, Prevnar-13
Asthma, asthma-like symptoms	Daptacel, FluMist, Gardasil/Gardasil 9, Pediarix, Pentacel, Tenivac, Vaqta	Engerix-B, Fluarix, Twinrix
Asthmatic crisis	Gardasil/Gardasil 9
Bronchial constriction	Vaqta
Bronchial hyperreactivity	Havrix
Bronchospasm, bronchial spasm	Daptacel, Gardasil/Gardasil 9, MMR-II, Prevnar-13, RotaTeq	Engerix-B, Fluarix, Flulaval, Gardasil/Gardasil 9, MMR-II, ProQuad, Recombivax, Tenivac, Twinrix
Cough	Afluria, Fluarix, Flucelvax, Flulaval, Fluzone, Gardasil/Gardasil 9, FluMist, MMR-II, ProQuad, Recombivax, Rotarix, Vaqta, Varivax	Fluarix, Fluzone, Infanrix, MMR-II, Pediarix, Pentacel
Cyanosis* [bluish discoloration, low oxygen]		Daptacel, Hiberix, Infanrix, Pediarix, Pentacel, Prevnar-13, Quadracel
Difficulty breathing		Menactra
Dyspnea [shortness of breath]	Prevnar-13	Fluarix, Flulaval, Fluzone, Havrix, Menomune, Pediarix, Quadracel, Twinrix
Dysphonia [vocal abnormalities]		Flulaval
Hypoxia	Daptacel, FluMist
Oropharyngeal pain	Afluria, Flucelvax, Flulaval, Gardasil/Gardasil 9	Fluzone, Menveo
Respiratory distress	Havrix	Fluarix
Rhinorrhea [runny nose]	Afluria, Fluarix, Flulaval, FluMist, Fluzone, HepB, MMR-II, ProQuad, Rotarix, Vaqta, Varivax	Fluzone
Stridor [high-pitched wheezing]		Fluarix
Throat tightness		Flulaval, Fluzone
Upper airway swelling		Menactra
Wheezing	FluMist, Menveo, Vaqta	Fluzone, Menactra, ProQuad
Skin/ subcutaneous tissue (33)	Acute hemorrhagic edema of infancy	MMR-II	MMR-II, ProQuad
Alopecia [hair loss]	Gardasil/Gardasil 9	Engerix-B, Recombivax, Twinrix
Contact rash	Varivax
Dermatitis	Vaqta, Varivax
Diaper rash	Varivax
Dry skin	Varivax
Eczema	Varivax	Engerix-B, Recombivax, Twinrix
Erythema [skin redness]	ActHIB, Adacel,Afluria, Bexero, Engerix-B, Flucelvax, Fluzone, IPOL, Menactra, Menveo, PedVaxHIB, Pneumovax-23, Prevnar-13, ProQuad, Quadracel, Recombivax, Twinrix, Vaqta, Varivax	Fluarix, Infanrix, Menactra, Menveo, MMR-II, Pediarix, Pentacel, Tdvax
Erythema multiforme [skin disorder]	Flucelvax, MMR-II, Prevnar-13	Engerix-B, Fluarix, Havrix, MMR-II, Pneumovax-23, ProQuad, Prevnar-13, Recombivax, Twinrix, Varivax
Erythema nodosum [nodules or lumps]	Gardasil/Gardasil 9	Engerix-B, Recombivax, Twinrix
Exanthem/viral exanthema [widespread rash]	ProQuad, Vaqta	Boostrix
Facial swelling/edema	Prevnar-13	Daptacel, Fluarix, MMR-II, ProQuad, Varivax
Heat rash	Varivax
Hyperhydrosis [abnormal sweating]		Flulaval, Havrix, Twinrix
Impetigo		ProQuad, Varivax
Lichen planus [inflammatory skin rash]		Engerix-B, Twinrix
Panniculitis [disease of fatty layer of skin]	MMR-II	MMR-II, ProQuad
Parotitis [salivary gland inflammation]	MMR-II	MMR-II, ProQuad
Pigmentation disorder	Gardasil/Gardasil 9
Pruritus [itchy skin]	Afluria, Engerix-B, Fluarix, Havrix, MMR-II, Pneumovax-23, ProQuad, Recombivax, Twinrix, Vaqta, Varivax	ActHIB, Adacel, Afluria, Boostrix, Daptacel, Fluarix, Flucelvax, Flulaval, Fluzone, Infanrix, Kinrix, Menactra, Menomune, Menveo, MMR-II, Prevnar-13, ProQuad, Tdvax, Tenivac
Psoriasis	Gardasil/Gardasil 9
Purpura [red/purple spots]	MMR-II	Engerix-B, MMR-II, ProQuad
Pustular psoriasis	Gardasil/Gardasil 9
Rash	Adacel, Afluria, Engerix-B, Flublok, Flulaval, Havrix, Menactra, Menomune, Menveo, MMR-II, PedVaxHIB, Prevnar-13, ProQuad, Recombivax, Twinrix, Vaqta, Varivax	ActHIB, Adacel, Afluria, Bexero, Boostrix, Daptacel, DT, Fluarix, Flucelvax, Flulaval, FluMist, Fluzone, Hiberix, Infanrix, IPOL, Menomune, MMR-II, Pediarix, Pentacel, Pneumovax-23, Prevnar-13, Quadracel, Tdvax, Tenivac
Rash morbilliform	Vaqta
Rash vesicular	ProQuad, Vaqta
Skin discoloration		Pentacel
Skin exfoliation		Menveo
Skin induration		MMR-II, ProQuad
Stevens-Johnson syndrome [severe skin reaction]	Gardasil/Gardasil 9, MMR-II	Engerix-B, Fluarix, Fluzone, MMR-II, ProQuad, Recombivax, Varivax
Sweating	Engerix-B, Fluarix, Flucelvax, Pneumovax-23, Recombivax, Twinrix
Vesiculation		MMR-II
Vitiligo	Gardasil/Gardasil 9
Vascular (10)	Cerebrovascular accident	Kinrix, Pneumovax-23, Tenivac	ProQuad, Varivax
Deep venous thrombosis		Gardasil/Gardasil 9
Flushing	Engerix-B, Recombivax, Twinrix	Flulaval, Fluzone
Henoch-Schönlein purpura [blood vessel inflammation]	MMR-II	Boostrix, Fluarix, MMR-II, ProQuad, Varivax
Pallor		DT, Flulaval, Hiberix, Pediarix, Pentacel, Prevnar-13, Quadracel
Petechiae [bleeding capillaries]	Engerix-B, Twinrix	Pediarix, Recombivax
Polyarteritis nodosa [damaged arteries]		Recombivax
Raynaud’s phenomenon	Gardasil/Gardasil 9
Renal vasculitis		Afluria
Vasculitis	MMR-II	Afluria, Engerix-B, Fluarix, Fluzone, Havrix, MMR-II, Recombivax, Twinrix
Urogenital (6)	Dysuria [difficult urination]	Recombivax
Epididymitis [testicular inflammation]	MMR-II	MMR-II, ProQuad
Orchitis [inflammation of the testes]	MMR-II	MMR-II, ProQuad
Proteinuria	Gardasil/Gardasil 9
Urinary retention	Pneumovax-23
Urinary tract infection	Gardasil/Gardasil 9, RotaTeq

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